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Find Ligands for your Target

Search for your target in the search bar above or Browse pharmacology groups below on tocris.com

Pharmacology Targets

GPCRs

Our comprehensive range includes agonists, antagonists, partial agonists, DREADD ligands, caged compounds, NAMs, PAMs, biased agonists and fluorescent probes targeting over 30 families of G protein-coupled receptors (GPCRs)/7-Transmembrane receptors (7-TMs), including 5-HT, Glutamate and Dopamine receptors.

Enzyme-Linked Receptors

Our expansive collection of small molecule and peptide ligands target both the receptor and enzyme components of the five main types of enzyme-linked receptors, including RTKs, RSTKs, and toll-like receptors.

 

Enzymes

Our expansive enzymes range includes activators, substrates, inhibitors and fluorescent probes targeting over 25 different enzyme families, including ATPases, hydrolases, phosphodiesterases and transferases.

Ion Channels

We offer an expansive collection of activators, blockers and modulators, PSEMs, and caged compounds that can manipulate several classes of ion channels including calcium channels, ligand-gated ion channels and potassium channels.

 

Nuclear Receptors

Our range of small molecules and peptides includes agonists, antagonists, modulators and fluorescent probes, which regulates the activity of over 20 types of nuclear receptors, including androgen, estrogen receptors, glucocorticoid and vitamin D receptors.

Transporters

Our transporter collection comprises inhibitors, activators, substrates and fluorescent probes, which target glucose, multidrug and neurotransmitter transporters, as well as ion pumps including Na+/Ca2+ exchangers and monocarboxylate transporters.

Other Pharmacology Targets

Targets include adenine receptors, antibiotics, antivirals, antioxidants, immunosuppressants, imidazoline receptors and sigma receptors among other targets, as well as miscellaneous compounds.

Antibodies

Antibodies

Bio-Techne brands R&D Systems and Novus Biologicals, offer 780,000 antibodies which have been validated in over 25 species for more than 15 applications.

Cell Adhesion Diagram with Extracellular Matrix Molecules, Extracts, and Substrates for Supporting Cell Adhesion and Growth of Neurons and Neurites

Electrophysiology

Electrophysiology techniques measure the electrical current or voltage changes across cells or tissue samples. Electrical activity can be modulated using ion channel modulators, DREADD ligands, PSEMs, GPCR ligands and caged compounds.

Immunoassays, ELISA kits and Luminex assays

Immunoassays

Bio-Techne offer a wide range of immunoassay kits and reagents, including, Luminex™ multiplexing assays, the gold standard Quantikine® ELISA kits, ELLA™ automated ELISA, and the Proteome Profiler™ Arrays.

Pharmacology Resources at tocris.com

Calculators

Use our calculators to plan your experiments: 

  • Molarity Calculators
  • Dilution Calculators
  • Reconstitution Calculators

Pharmacology Glossary

  • Clear definitions
  • Common equations
  • Defined constants

Literature

  • Scientific Posters
  • Scientific Reviews
  • Product Guides
  • Research Bulletins
  • Scientific Meeting Posters

Background Information

TcBuster graphic

Gene Engineering Services

Let us solve your gene engineering challenges so you can focus on groundbreaking research. Our gene engineering services team specializes in complex projects and hard-to-transfect cell lines.

For cell and gene therapy manufacturing, we offer GMP CDMO services that include process development for cell engineering, quality control, custom cell vialing, and regulatory support.

View Our Gene Engineering Services